If you’ve recently been written a prescription for Ozempic, or if you’re looking to purchase a supply for future use, you may have questions about its dosage. While every situation is unique, most patients treated with Ozempic follow a similar dosage progression.

Below, we’ll cover some Ozempic basics—what it is, why it’s prescribed, its forms, strengths, and standard dosing schedule, as well as its potential risks and side effects. We’ll finish off with some frequently asked questions to provide you with a clear overview.

None of the information here constitutes medical advice. It’s only intended to supplement information from your primary healthcare provider and help you better plan for procuring the correct dosages of Ozempic in the future. Always contact your doctor with any specific questions or concerns.

Ozempic Forms

Ozempic is a liquid solution in pre-filled injectable pens. Each pen contains several doses of medication and comes with enough fresh needles to administer all of them. Ozempic pens are for single-patient use and should never be shared between patients.

Ozempic Strengths

Ozempic pens come in three strengths:

  • Ozempic 0.25 mg or 0.5 mg dose (2 mg/1.5 mL subcutaneous pen injector)
    • 0.25 mg initial dose is injected weekly for 4 weeks, followed by 2 weeks of 0.5 mg injections to build up a tolerance.
    • To maintain a 0.5 mg dosage, continue injections once weekly (each pen contains enough medication for 4 injections).
  • Ozempic 1 mg dose (4 mg/3 mL subcutaneous pen injector)
    • To maintain a 1 mg dosage, continue injections once weekly (each pen contains enough medication for 4 injections).
  • Ozempic 2 mg dose (8 mg/3 mL subcutaneous pen injector)
    • To maintain a 2 mg dosage, continue injections once weekly (each pen contains enough medication for 4 injections).

Recommended Ozempic Dosages

The dose of Ozempic recommended for you by your doctor will be determined by your personal needs and response to the medication. Not all patients require the same weekly dosing schedule, and healthcare providers will observe patients carefully to ensure that treatment is progressing appropriately. Your doctor will typically start you at a low dosage and slowly increase it to build up your body’s tolerance to the drug.

A standard weekly administration schedule is outlined below, but remember to follow the specific plan laid out for you by your own doctor and pay close attention to any adverse reactions:

  • Begin with a dose of 0.25 mg once weekly for 4 weeks.
  • Increase your dosage to 0.5 mg once weekly for 4 more weeks.
  • After 4 weeks on a 0.5 mg once weekly dose, your doctor will assess your glucose control. You may remain on a 0.5 mg once weekly dose or your dose may be increased to 1 mg or even 2 mg once weekly.

Where To Inject Ozempic

The best injection sites for Ozempic are the stomach (abdomen), thigh, or upper arm. None of these sites is medically superior to the others, but you may personally prefer one over the rest. Recommended best practice is to rotate injection sites each week. If you do opt to use the same site more than once in a row, use a different part of the site to reduce irritation in the area as a whole.

Ozempic is injected subcutaneously (under the skin) and should never be injected intramuscularly or intravenously.

While it’s possible to inject Ozempic and insulin at the same site, the two medications should never be mixed and should be injected in different areas of the site. Don’t use the same needle to inject Ozempic and insulin.

What Is the Best Time Of Day To Inject Ozempic?

Medically speaking, it doesn’t really matter what time of day you take Ozempic. Ozempic should be injected once per week on the same day of the week, but Novo Nordisk clearly states that the drug can be taken “at any time of day, with or without meals”.

That being said, you may find that a specific time of day is best for you personally. Even though you can technically take Ozempic at any time of day, most patients find that creating a consistent routine is helpful.

Schedule your Ozempic injection to suit your timetable and rhythms. Make sure it’s at a time when you’re home, alert, comfortable, and don’t have any conflicting commitments. Writing injections on your calendar is a good idea, as is programming an ongoing reminder into your smartphone.

As your body adjusts to Ozempic, you may find that it’s easiest for you to inject with or without food or at a specific time of day. You can always modify your injection schedule accordingly.

You can generally change the day of the week you inject Ozempic as long as you leave at least two days between shots. But it’s always a good idea to consult with your doctor before making any such change to your medication routine.

How Do I Know If My Ozempic Pen Is Empty?

You should have a good sense of when your Ozempic pen will run out because you will know how many doses are contained in your pen and how many doses you have taken. The 1 mg and 2 mg pens are very straightforward. As you titrate up from a starting dose of 0.25 mg to a 0.5 mg dose, you may have to keep track a little more carefully. At Bisonpharmacy.com, we highly recommend planning ahead to ensure that you allow time to order and receive a new Ozempic pen before your current one runs out.

If you cannot dial up your dose counter to the desired dose, this indicates that your pen is either completely empty or does not have enough Ozempic remaining to meet your dose requirements.

What Happens If You Use Ozempic After 56 Days?

The main risk of using Ozempic which has been open for more than 56 days, is the reduced potency and efficacy of the drug. This could mean less effective blood sugar control, putting you at risk for hypoglycemia or other serious outcomes. It could also cause dysregulation in your overall health and interrupt your weight management progression.

In addition to the concerns associated with injecting Ozempic that has lost potency, there is also the potential for bacterial contamination as Ozempic ages. It is important to take proper precautions and dispose of expired Ozempic immediately to avoid the risk of serious harm.

Sometimes in life, it can feel like there are a million things to keep track of appointments, meetings, social events, work functions, and all the day-to-day obligations like errands, food prep, and more. If you are currently taking Ozempic or have recently received a prescription for it, you’ll be keeping track of that too.

Using Ozempic Long-Term

Ozempic is meant to be a long-term medication, so if you’ve been prescribed Ozempic, you’ll likely be looking at taking it for a long time. Side effects tend to diminish as your body adjusts to the medication over time, and you may use the drug as long as it continues to effectively treat the conditions your doctor has prescribed it for.

Potential Side Effects

Side effects may occur when starting Ozempic but should decrease as your body adjusts to increased dosages. Common side effects include nausea, vomiting, diarrhea, constipation, and stomach pain.

Discuss any concerns with your primary healthcare provider, and be sure to disclose any other medications you may be taking (including herbal supplements). Ozempic is not recommended for pregnant women.

Risks & Warnings

Though rare, serious side effects are possible with Ozempic. Major warning signs to watch for include pancreatitis (persistent severe abdominal pain), vision problems (diabetic retinopathy complications), reduced renal function, and serious hypersensitivity reactions such as swelling of the tongue, lips, or face, fainting, or a racing pulse. If any hypersensitivity reactions occur, contact your doctor or call 911 immediately.

In addition, it’s advised not to use Ozempic if you have a personal or family history of Medullary Thyroid Carcinoma (MTC) or if you’re at increased risk of Multiple Endocrine Neoplasia Syndrome Type 2 (MEN 2). Patients should be referred to an endocrinologist for further evaluation if serum calcitonin is measured and found to be elevated or thyroid nodules are noted on physical examination or neck imaging.

FAQ

What’s Ozempic’s Dosage Per Pen?

Ozempic pens come in different strengths and dosages, depending on your prescription. You’ll typically begin with a low dose and gradually build up to higher doses to increase tolerance and decrease side effects.

  • The 0.25 mg or 0.5 mg strength comes in a pen that contains up to 6 doses.
  • The 1 mg strength comes in a pen that contains 4 doses.
  • The 2 mg strength comes in a pen that contains 4 doses.

Does Ozempic Require A Prescription?

Yes. Ozempic is a prescription drug for treating Type 2 Diabetes and related cardiovascular conditions in adults. If you plan to use Ozempic for another purpose, such as weight loss, your doctor will need to write you an “off-label” prescription.

Wegovy, a similar semaglutide drug that has been approved for weight loss, also requires a prescription from a doctor.

How Do I Use Ozempic?

Ozempic is administered once per week subcutaneously (under the skin of the stomach, abdomen, thigh, or upper arm). The standard protocol is to begin with a lower starting dose (0.25 mg) and build up to a higher dose (0.5 mg, 1 mg, or 2 mg) to increase tolerance and reduce side effects.

In consultation with your doctor, you’ll be shown how to cleanse the injection site, attach a clean needle to the Ozempic pen, select the correct dose using the dose counter dial, inject Ozempic, safely dispose of the needle, and properly store the remaining Ozempic for future injections.

See also: When To Stop Ozempic Before A Colonoscopy.

What If I Miss A Dose?

Ozempic is typically self-injected once per week, on the same day of the week, with or without a meal. A missed dose should be taken as soon as possible, any time up until 5 days after the day it was originally supposed to be administered. After 5 days have passed, the dose is skipped entirely, and the next dose is taken on the correct day of the following week.

Conclusion

Ozempic is a prescription drug that’s used to treat Type 2 Diabetes and underlying cardiovascular conditions. Many patients treated with a weekly administration of Ozempic experience a rapid improvement in glycemic control and weight loss management.

While every patient is unique, Ozempic dosage typically follows a standard schedule, building up a tolerance to the medication over a series of weeks before arriving at a therapeutic dose for long-term maintenance.

If you’re looking to order Ozempic from Canada, discuss your dosage progression with your doctor first so that you can purchase the correct Ozempic pens for your needs.

Ordering Canadian Ozempic through Bisonpharmacy.com is a game-changing option. Bisonpharmacy.com is a prescription referral service that partners with reputable Canadian pharmacies to provide quality pharmaceuticals to Americans at affordable prices.

Contact Bisonpharmacy.com today to order Ozempic from Canada online!

About the Author

Ida Edlweiss Gumpal is a licensed Pharmacist and medical writer. She took her internships at Mercury Drug Corporation, Inc., a Hospital internship at De Vera Medical Center, Inc., and a Manufacturing internship at Philmed Laboratories, Inc. She has plans on attending medical school with the goal of specializing in Neurosurgery or Cardiothoracic surgery.